How to beat Karthus with Master Yi Click here for How to beat Master Yi with Karthus
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Karthus has no way to stop Master Yi's chase. Kill him and quickly run away as his Death Defied will keep him alive for 7 more seconds. Don't underestimate his damage late game! Report
3
When Karthus ults, use your Alpha Strike to deny all damage from it. Worst case scenario, you can still use your Meditate to tank it. Report
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When Karthus activates his Ultimate Requiem, Yi can use his "W" meditate and reduce the Damage from the Ultimate significantly! Report

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